Brookline Place is situated prominently at the intersection of Brookline Avenue, Route 9, and Route 1 (the Riverway) in Massachusett's renowned Longwood Medical Area. Brookline Place is across the street from the
Brookline Village stop on the Riverside (D) Branch of the MBTA's Green Line, as well as stops on the 65 and 66 bus lines.
Mass Pike Eastbound - take Brighton-Allston exit (a left exit) after the toll booths; bear to the right and proceed down a ramp, and through one light to the corner where the DoubleTrees Inn is on your right. Turn right and enter Storrow Drive eastbound. Take the Fenway exit and bear right at the first light onto Boylston Street westbound. Proceed on Boylston westbound for less than a mile. At the major five-way traffic lights, bear left onto Brookline Avenue.
*Continue for 1.5 miles past the Longwood Hospital area into Brookline. Watch for Pearl Street on the right after a baseball field. Turn right onto Pearl Street, and take an immediate left into the circle driveway at the main entrance to One Brookline Place. The garage may be entered here, also.
Route 93- go to Storrow Drive. Take the Fenway exit, follow Brookline Avenue, following directions(*) above.
Route 128- go to Route 9, continue eastbound until you come to Brookline Village. Take a left onto Brookline Avenue, where Brookline Place is situated.