One Brookline Place is part of the larger Brookline Place development, which includes 414 parking spaces in an above-ground garage and open-air parking lot, a Bertucci's restaurant, banking, food and other business and personal services. The development has 24x7 security and is within walking distance to the MBTA Green Line (both Riverside and Arborway) and Brookline Village. The development has direct access to Route 9 and the Longwood Medical and Academic Area (LMAA).